2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N18774
    Commiphora mukul extract 93165-11-8
    Commiphora mukul extract is rich in active ingredients, such as phytosterols, guggul lipids, and guggulsterones (particularly guggulsterones). Commiphora mukul extract can be used in obesity research.
    Commiphora mukul extract
  • HY-N19039
    Aerva lanata extract 98%
    Aerva Lanata Extract is a versatile herbal extract with a wide range of bioactive compounds and medicinal properties. Aerva Lanata Extract contains various phytochemicals such as flavonoids, terpenoids, alkaloids, tannins, and phenolic compounds. Aerva Lanata Extract shows significant antioxidant, antimicrobial, anti-cancer, anti-inflammatory, and anti-diabetic activities.
    Aerva lanata extract
  • HY-N19059
    Boerhavia diffusa extract
    Boerhavia diffusa extract contains a variety of bioactive compounds, including alkaloids, flavonoids, and glycosides. It can protect kidney and liver health and has diuretic and detoxifying effects.
    Boerhavia diffusa extract
  • HY-N19062
    Caralluma fimbriata extract 98%
    Caralluma fimbriata extract is often used to suppress appetite and aid in weight management.
    Caralluma fimbriata extract
  • HY-N19068
    Crataeva nurvula extract 98%
    Crataeva nurvula extract is rich in active ingredients including flavonoids, saponins, triterpenoids, alkaloids, and tannins. Crataeva nurvula extract helps promote healthy kidney and bladder function.
    Crataeva nurvula extract
  • HY-N19069
    Eugenia jambolana extract
    Eugenia jambolana extract, commonly known as jamun or black plum, is derived from the fruit of the Eugenia jambolana tree, native to South Asia. The active compounds in jamun extract include anthocyanins, flavonoids, alkaloids, and tannins, which contribute to its antioxidant, anti-inflammatory, and antimicrobial properties. Jamun extract is most known for its blood sugar-lowering effects, making it popular in traditional medicine for managing diabetes. It is commonly used in supplements, traditional remedies, and skincare products due to its wide range of health benefits.
    Eugenia jambolana extract
  • HY-N19070
    Ginko biloba extract
    Ginko biloba extract is derived from the leaves of the ginkgo tree, and its main active ingredients include flavonoids (such as quercetin and kaempferol) and terpenoids (such as ginkgolide and ginkgolide).
    Ginko biloba extract
  • HY-N19131
    Aquastatin B 160219-85-2 98%
    Aquastatin B is a PTP1B inhibitor. Aquastatin B is isolated from marine fungi. Aquastatin B exhibits anti-diabetic activity. Aquastatin B can be used in the research of diabetes.
    Aquastatin B
  • HY-N19223
    Spongipregnoloside B 552297-98-0 98%
    Spongipregnoloside B is a pregnane diglycoside found in the rhizomes of Dioscorea spongiosa. Spongipregnoloside B can be used in osteoporosis research.
    Spongipregnoloside B
  • HY-N1932R
    Bayogenin (Standard) 6989-24-8
    Bayogenin (Standard) is the analytical standard of Bayogenin (HY-N1932). This product is intended for research and analytical applications. Bayogenin is a triterpenoid saponin and one of the main components of Medicago sativa saponins. Bayogenin is an inhibitor of glycogen phosphorylase.
    Bayogenin (Standard)
  • HY-N19425
    Pulsatilloside A 136684-41-8
    Pulsatilloside A is an anti-Apoptotic agent. Pulsatilloside A can be isolated from the roots of P. chinensis. Pulsatilloside A exerts a protective effect against apoptosis induced by sodium cyanide and glucose deprivation.
    Pulsatilloside A
  • HY-N1957R
    Gamma-Mangostin (Standard) 31271-07-5 98%
    Gamma-Mangostin (Standard) is the analytical standard of Gamma-Mangostin. This product is intended for research and analytical applications. Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer. Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes.
    Gamma-Mangostin (Standard)
  • HY-N19646
    [8]-Dehydrogingerdione 77334-08-8 98%
    [8]-Dehydrogingerdione is a Hydroxyphenylalkanone. [8]-Dehydrogingerdione can be isolated from the seeds of Aframomum melegueta and the rhizomes of Curcuma xanthorrhia. [8]-Dehydrogingerdione acts as an inhibitor of α-glucosidase and Tyrosinase, with an IC50 value of 19.5 μM against α-glucosidase and an approximate IC50 value of 100 μM against tyrosinase. [8]-Dehydrogingerdione can be used in diabetes-related research.
    [8]-Dehydrogingerdione
  • HY-N1964A
    Gibberellic acid, suitable for plant cell culture 77-06-5 98%
    Gibberellic acid, suitable for plant cell culture (GA3, suitable for plant cell culture) is a natural plant growth regulator with oral bioactivity. Gibberellic acid, suitable for plant cell culture governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid, suitable for plant cell culture optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid, suitable for plant cell culture mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid, suitable for plant cell culture can be used in studies of plant growth, metabolism, and abiotic stress responses.
    Gibberellic acid, suitable for plant cell culture
  • HY-N1964B
    Gibberellic acid Sterile Solution (1 mg/ml) 98%
    Gibberellic acid Sterile Solution (1 mg/mL) (GA3 Sterile Solution (1 mg/mL)) is a natural plant growth regulator with oral bioactivity. Gibberellic acid Sterile Solution (1 mg/mL) governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid Sterile Solution (1 mg/mL) optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid Sterile Solution (1 mg/mL) mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid Sterile Solution (1 mg/mL) can be used in studies of plant growth, metabolism, and abiotic stress responses.
    Gibberellic acid Sterile Solution (1 mg/ml)
  • HY-N1964R
    Gibberellic acid (Standard) 77-06-5
    Gibberellic acid (Standard) is the analytical standard of Gibberellic acid (GA3) (HY-N1964). This product is intended for research and analytical applications. Gibberellic acidis a natural plant growth regulator with oral bioactivity. Gibberellic acid governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid can be used in studies of plant growth, metabolism, and abiotic stress responses.
    Gibberellic acid (Standard)
  • HY-N19669
    27-Hydroxyisomangiferolic acid 123563-64-4
    27-Hydroxyisomangiferolic acid, a cycloartane-type triterpene found in Indonesian propolis from East Java, acts as a weak scavenger with low free radical scavenging activity against DPPH (HY-112053) radicals. can be used for research on inflammation, heart disease, diabetes and cancer.
    27-Hydroxyisomangiferolic acid
  • HY-N19683
    Kaempferol-3-O-a-L-(3'',4''-di-Z-p-coumaroyl)-rhamnopyranoside 1067238-40-7 98%
    Kaempferol-3-O-a-L-(3'',4''-di-Z-p-coumaroyl)-rhamnopyranoside is a 3-O-(coumaroyl-rhamnopyranosyl)-flavonol compound found in the leaf extract of Machilus philippinense Merr..
    Kaempferol-3-O-a-L-(3'',4''-di-Z-p-coumaroyl)-rhamnopyranoside
  • HY-N19715
    Asperosaponin H1 159993-47-2 98%
    Asperosaponin H1 is a triterpenoid saponin (octasaccharide saponin) found in the roots of Dipsacus asperoides C.Y. Cheng et T.M. Ai. Asperosaponin H1 can be used for research on liver and kidney diseases.
    Asperosaponin H1
  • HY-N19725
    Calonysterone 51787-31-6
    Calonysterone is an orally effective IL-6 inhibitor. Calonysterone reduces the level of the proinflammatory cytokine IL-6. Calonysterone prevents diet-induced obesity. Calonysterone normalizes abnormal plasma adiponectin and leptin concentrations. Calonysterone increases the percentage of total DNA methylation. Calonysterone enhances antioxidant activity. Calonysterone is applicable to obesity-related research.
    Calonysterone
Cat. No. Product Name / Synonyms Application Reactivity